A new isolation with migration model along complete genomes infers very different divergence processes among closely related great ape species.
We present a hidden Markov model (HMM) for inferring gradual isolation between two populations during speciation, modelled Acteoside and ursolic acid synergistically protects H2O2-induced neurotrosis by regulation of AKT/mTOR signalling: from network pharmacology to experimental validation as a time interval with restricted gene flow.The HMM descri